The Hauptfriedhof is actually the largest cemetery in Frankfurt, and was opened in 1828. There are quite a few famous and important people buried here, including Arthur Schopenhauer and Alois Alzheimer. I found a map at the entrance and so I used that to try to follow paths and identify the graves of some notable personalities.
There weren't plenty of visitors when I was there on a Saturday morning. Nevertheless, there were older visitors who were taking care of the graves of their loved ones: watering the plants, clearing the weeds, and in general taking care of the overall area. It was a hot day, but in any case it was a nice outdoor walk methinks.